We offer the widest product range of low-flow (mass) flow meters and controllers on the market. Numerous styles of both standard and bespoke instruments can be offered for applications in laboratory, machinery, industry and hazardous areas.
Customer satisfaction, innovation and quality of product and service have been the cornerstones of Bronkhorst's success. Based on our experience, innovation and sense of responsibility, a relationship with Bronkhorst assures Performance for Life.
Bronkhorst instruments are used for numerous applications in many different markets. In this section you will find an overview of the main markets for our equipment, illustrated with some typical examples of applications.
Are you looking for technical documentation, are you interested to learn more about the measuring principles of Bronkhorst products, or you do want to get in contact with a Bronkhorst Service Engineer? This section will guide you to the relevant service & support topics.
Bronkhorst High-Tech BV the leaders in Mass Flow Meter / Mass Flow Controller technology for gases and liquids, Pressure Controllers and Evaporation Systems.
Patients who suffer from liver tumours that
cannot be surgically removed nor respond to
chemotherapy, may benefit from a local treatment
with radioactive particles.
Quirem Medical manufactures polylactic acid
microspheres containing radioactive holmium,
suitable for such treatment. These microspheres are
injected in the hepatic artery and are carried along
by the blood flow. The radioactive microspheres will
lodge within the small blood vessels near the liver
tumour where they deliver their radiation locally,
with the aim to kill the tumour cells. Quirem Medical
manufactures the non-radioactive microspheres.
Subsequently, the microspheres are enriched by
neutron bombardment. An essential step in the
synthesis is the controlled evaporation of a solvent
that has been used in a previous step. Bronkhorst
mass flow controllers deliver the nitrogen flow to
enhance and control the solvent evaporation.
Nitrogen is needed to evaporate the solvent, as it
acts as an inert carrier gas that sweeps off the
evaporated solvent and accordingly determines the
evaporation rate. So the correct nitrogen flow is a
very important parameter in the production
process to obtain the right size of the microspheres.
To evaporate the solvent in the microsphere synthesis, classic type EL-FLOW mass flow controllers are used. There are five batch processes in parallel, each with its own mass flow controller and with a Hepa filter upstream. All of these mass flow controllers have FDA approved seals, to anticipate future use of the product in the USA. These mass flow controllers were manufactured in the cleanroom, and were double packed and sealed delivered. This delivery included all necessary certifications, including a TSE/BSE declaration to demonstrate that no animal fats have been used in the device. Moreover, Bronkhorst MASS-VIEW has been included, to monitor if the mass flow controllers will deviate in due time, which may be a trigger to send the devices to Bronkhorst for recalibration. The correct nitrogen flow is a very important parameter in the production process. The scale of the flow is for Quirem Medical more important than its accuracy. Furthermore, a high quality flow controller (and meter) is necessary: to establish a stable flow, and also to be able to monitor the process conditions - for read out and data storage. They are pleased with the mass flow controller, and satisfied with Bronkhorst’s fast service.
The currently used flow is very suitable to produce microspheres that are used to treat patients. Perhaps in the future will be investigated if a different nitrogen flow rate results in an improvement of the production process.
NL-7261 AK Ruurlo (NL)
Tel. +31 573 458800