Flow and pressure control
The control of gas flow, liquid flow and pressure are 3 important functionalities to consider when working with lung-on-a-chip applications:
- Pressure control, where (sub-atmospheric) pressure differences (“vacuum”) can be applied to the side chambers to mimic the stretching of the lung cells when breathing; pressure range is -100 .. -600 mbarg (with respect to atmospheric pressure)
- Gas flow control, which nimics the oxygen supply to the lung cells; flow range is 1 – 20 mln/min of air
- Liquid flow control, where the blood-like liquids and nutrition can be provided to the lung cells, and where the blood circulation can be mimicked; flow range is 1 - 50 µl/min
Bronkhorst has an extensive product line with instruments for flow
control that are a perfect fit for these flow and pressure rates.