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Learn more about how Coriolis-based flow meters can be used as microfluidic flow meter instead of thermal flow meters. Read the customer story of a microfluidics system builder who used Bronkhorst products.
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Bronkhorst High-Tech BV the leaders in Mass Flow Meter / Mass Flow Controller technology for gases and liquids, Pressure Controllers and Evaporation Systems.
Working in flow, specifically low flow solutions, brings you into contact with applications and challenges that can be quite surprising. This week we discuss an opportunity for new calibration techniques to prove infusion pump performance.
Infusion pumps are well-known in medical applications. They come in multiple operating principles for pumping various fluids.
We learned from users that the readout of a syringe pump shows the set point flow but it gives no feedback on the actual flow. Because of this lack of feedback on the actual flow being delivered, it is an area that should require regular accuracy checks. A regular programme of checks at a pre-determined flow rate or range is essential for ensuring that the delivery of fluid from the pump matches the expectations of the user. This is also an excellent opportunity to data log the performance of the pump for future reference and assists management purposes.
Moreover, we learned from medical engineering groups that there are currently two main calibrating techniques available for infusion pumps;
To define the value of this study we identified together with the working groups potential applications in which accurate dosing is a critical process parameter. Below you will find the applications as identified:
We defined the hypothesis that the characteristics of a low flow Coriolis sensor could support the scope to improve the accuracy and response time of calibration systems used to calibrate syringe pumps. We demonstrated the validity of this hypothesis during an in-house study and at a hospital in the Netherlands. The Coriolis principle chosen due to its proven accuracy and long term stability. Furthermore, due to their small internal volume and little pressure drop these instruments can be used in line to test complex multi infusion systems.
We bench marked the Coriolis sensor technique against an electronic analytical balance in house. The set-up of this experiment was approved by the Dutch Accreditation Council. Furthermore, we performed a bench mark study against an infusion calibration system at a hospital in the Netherlands.
The results of this study confirmed that the Coriolis sensor techniques can surpass the accuracy and response time of the incumbent measurement principles used in calibration systems.