We offer the widest product range of low-flow (mass) flow meters and controllers on the market. Numerous styles of both standard and bespoke instruments can be offered for applications in laboratory, machinery, industry and hazardous areas.
Customer satisfaction, innovation and quality of product and service have been the cornerstones of Bronkhorst's success. Based on our experience, innovation and sense of responsibility, a relationship with Bronkhorst assures Performance for Life.
Bronkhorst instruments are used for numerous applications in many different markets. In this section you will find an overview of the main markets for our equipment, illustrated with some typical examples of applications.
Are you looking for technical documentation, are you interested to learn more about the measuring principles of Bronkhorst products, or you do want to get in contact with a Bronkhorst Service Engineer? This section will guide you to the relevant service & support topics.
Bronkhorst High-Tech BV the leaders in Mass Flow Meter / Mass Flow Controller technology for gases and liquids, Pressure Controllers and Evaporation Systems.
In bioreactors delicate processes take place to multiply biological materials. These processes contain valuable substances, sometimes even beyond a price tag, as these can be an important step in a new vaccine or treatment.
Our commitment to our customers in the biotech industry is to make bioreactors work with reliable and reproducible mass flow controllers.
For this blog we interviewed Dion Oudejans and Vincent Hengeveld, Product Managers at Bronkhorst about reliable flow controllers.
Reliability refers to the quality of being able to be trusted to do what somebody wants or needs (Definition Oxford dictionary). Vincent and Dion explain that our commitment to reliability is built on various pillars.
By providing the most reliable mass flow instruments - using robust sensors and valves with stable electronics and firmware¸ documented in material certificates - high accuracy which is documented in calibration certificates and best in class mean-time-between-failure (MTBF) data based on the IEC 61508 standard, the quality can be quaranteed.
Could you explain what the high accuracy statement means and why this is an important selection criteria for our customers in the biotech industry?
Optimal accuracy and ratios are required to allow the biological substance to grow in the right environmental conditions. During a bioreactor campaign, biological substance grows over time and requires an increasing flow rate during the growth process. Both low and high gas flow rates are needed.
For these applications Bronkhorst offers mass flow controllers, based on reliable and accurate capillary bypass technology and valve technology, which can achieve a dynamic flow range of up to 1 : 200, providing the low and high flow rates required for the growth process.
Mass flow controllers which are built with capillary bypass technology have a tube-shaped flow sensor inside that is positioned parallel – in bypass – with the main flow path. There is an accurate split of gas flow into the flow sensor and the main flow path, see picture [flow sensor used in the capillary bypass technology]. This particular technology enables reliable and accurate flow measurement and control for all different gases involved.
Only a part of the gas stream flows through the sensor and is warmed up by two heater elements (RHT1 and RHT2). The gas flow through the flow sensor is a proportional measure for the total flow through the instrument. Due to the homogeneous nature of the temperature distribution within the sensor, only the flow rate, the density and the heat capacity of the gas determine the flow output signal (Q, ρ, Cp).
Conversion factors (ρ۰Cp) can be applied to calculate the flow rate of gases other than the calibration gas.
Mean Time Between Failures (MTBF) is used as a measure for availability and reliability of products. MTBF predicts the time that equipment is operating between breakdowns or stoppages. There are several methods of calculating the MTBF rating, with the IEC 61508 based on the Exida component database being the industry standard. With an MTBF rating of over 130 years for the major biotech industry product lines, we are best-in-class.
Easy field calibration with Air/N2, thanks to accurate conversion method and free software tools, supports our customer base to maintain the high accuracy documented in the calibration certificate provided at arrival of the mass flow controller.
Check our bioreactor market page for more information about flow meters and controlles for bioreactor and ferementation.
Especially for the valuable processes as these, it is very helpful if you can monitor the ‘health’ of your instruments, to ensure the continuity of the process. For this several parameters & diagnostics are interesting:
Reliable gas flow control in bioreactor processes is crucial to allow the biological substance to grow in the perfect environmental conditions. Using automated instruments, such as flow controllers, with intelligent parameters can help you ensure the continuity of the process.
Bronkhorst digital mass flow controllers offer a range of parameters for extended measurement, control and diagnostics functionality, such as:
Do you know what the biotechnology is? Read it in our new blog and learn more about the solutions for bioprocessing and bioreactor with mass flow meter in a bioreactor or fermenter market.
The importance of effective maintenance, corrective maintenance and preventive maintenance for flow meters and flow controllers.
Read the inspiring guest blog from Jornt Spit, researcher at the ‘Radius research group’ at Thomas More University of Applied Sciences (BE), about research towards renewable biomass.